The Iron Mountain Trail
(#301) runs the length of the Mount Rogers National Recreation Area from Damascus, VA to Fries, VA following a historical alignment of the Appalachian Trail (i.e great singletrack!).
This segment is a no-nonsense singletrack through a dense forest in a little-used part in the eastern half of the Mount Rogers National Recreation Area. The area is probably more popular with equestrians than runners, so be on the lookout for horses, but don't let that scare you off.
The trail is heavily forested so aside from the occasional break in the forest, you won't have much to see but the long, winding singletrack in front of you.
This segment links with another portion of the Iron Mountain Trail
to the west. To continue east, you'll have to take Divide Trail #309
and the Virginia Highlands Horse Trail to reach the final segment: The Iron Mountain Trail
#301(IMT): State Road 653 to 644.